糖化血红蛋白HbA1c抗体

糖化血红蛋白（GHb）是血液葡萄糖通过非酶作用，经细胞膜与红细胞内血红蛋白-链颉氨酸结合形成的产物，其合成速率与红细胞所处环境中糖的浓度成正比。糖化血红蛋白的形成是不可逆的，其浓度与红细胞寿命（平均120天）和该时期内血糖的平均浓度有关，不受每天血浆葡萄糖浓度大小波动而变化，也不受运动或食物的影响。因此糖化血红蛋白是反映过去6~8周的平均血糖浓度，GHb由HbA1a、HbA1b、HbA1c组成,其中HbA1c约占70%,且结构稳定,因此被用作糖尿病控制的监测指标。HbA1c采用亲和色谱或高效液相色谱测定，其浓度用占成人血红蛋白的百分比表示，正常值为4%～6%。

糖化血红蛋白（HbA1c）是评估长期血糖控制状况的金标准，2020年《中国2型糖尿病防治指南》将HbA1c纳入糖尿病的诊断标准。关于糖化血红蛋白，你知道多少？糖化血红蛋白与糖化白蛋白，有何区别？葡萄糖目标范围内时间（TIR），如何用于降糖药治疗方案的调整？1. 糖化血红蛋白是什么？糖化血红蛋白，是血液中的葡萄糖与红细胞中的血红蛋白不可逆结合的产物，随红细胞消亡而消失。

HbA1c is very important for people who are at risk for diabetes or for those that have already been diagnosed with the condition. People with diabetes should have their blood sugar levels tested regularly to know the status of their condition. Unlike the blood glucose test, which measures the glucose at that exact moment, the HbA1c levels say something more about the glucose levels in the last few months.

This is because red blood cells with Hba1c in them can live up to 2-3 months. That way, the HbA1c levels give a better indication of the blood sugar level over a longer period of time, making the test more qualified to check if diabetes is actually under control. Managing diabetes is very important because uncontrolled diabetes can have severe consequences such as eye and kidney disease.

HbA1c, as a clinical marker of glycemic control, has certain limitations and restrictions. Because of the long lifespan of erythrocytes of about 120 days [317], glycation modifications accumulated over a similar long-time period. HbA1c reflects average blood glucose levels over the previous 2–3 months [318,319]. Therefore, rapid changes in glycemic status, for example, in response to treatment, are not well reflected in HbA1c measurements

Abgree提供优化后的糖化血红蛋白抗体，不含任何添加防腐剂，经过客户临床样本验证，HbA1c抗体可以较好的应用于免疫层析和胶乳增强免疫比浊法等