May 27, 2022
HbA1c antibody， Mouse anti-Hba1c antibody
Glycated hemoglobin (GHb) is a product formed by the non-enzymatic action of blood glucose through the combination of hemoglobin and hemoglobin in red blood cells through the cell membrane, and its synthesis rate is proportional to the concentration of sugar in the environment where the red blood cells are located. The formation of glycated hemoglobin is irreversible, and its concentration is related to the lifespan of red blood cells (average 120 days) and the average blood glucose concentration during this period, and is not affected by daily fluctuations in plasma glucose concentration, nor by exercise or food. Therefore, glycated hemoglobin reflects the average blood glucose concentration in the past 6 to 8 weeks. GHb is composed of HbA1a, HbA1b, and HbA1c, of which HbA1c accounts for about 70%, and its structure is stable, so it is used as a monitoring indicator for diabetes control. HbA1c is determined by affinity chromatography or high performance liquid chromatography, and its concentration is expressed as a percentage of adult hemoglobin, and the normal value is 4% to 6%
Abgree provides optimized glycosylated hemoglobin antibodies, which have been verified by customers' clinical samples and can be better used in immunochromatography and latex-enhanced immunoturbidimetry.