环瓜氨酸肽CCP

货号：C7021

简介：
The presence of anti-CCP antibodies has a specificity of >90% for RA. When used in combination with the rheumatoid factor assay, the positive predictive value approaches 100%. They may be detected years before the onset of clinical symptoms of RA. Its presence is also associated with the severity of the disease at the time of diagnosis. Since the presence of anti-CCP early in the disease is associated with an increased risk of joint erosion, more aggressive therapy may be indicated than in anti-CCP negative cases. The RA-7 revised criteria for the diagnosis of RA by the American College of Rheumatology improved the sensitivity without decreasing specificity by replacing the requirement for rheumatoid nodules with a positive anti-CCP test result